High-resolution clonal tracking and vector integration analysis — from preclinical development to clinical monitoring — powered by over two decades of ISA expertise.
The ISA Core is an end-to-end platform designed to support vector safety assessment and high-resolution clonal tracking across gene and cell therapy programs. Positioned within one of Europe's leading gene therapy clinical centres, we believe this is the first UK-based ISA core offering a fully integrated, clinical-grade workflow.
"Seamlessly operational across preclinical and clinical development pipelines."
Our integration site analysis services span the full spectrum of gene and cell therapy approaches, from ex vivo modification to in vivo delivery.
Starting from cell pellets or genomic DNA, our end-to-end pipeline integrates optimised sample processing, next-generation sequencing, and validated bioinformatic analysis into a single, cohesive service.
Every deliverable is tailored for meaningful decision-making — whether that's regulatory filing, clinical monitoring, or publication.
We also offer custom analyses aligned with regulatory and translational needs, with experience supporting IND-enabling studies, clinical monitoring, and long-term follow-up programs.
Whether you are looking to de-risk vector integration profiles, monitor clonal dynamics, or strengthen your safety package — we would welcome the opportunity to discuss how we can support your program.